Drugs / Levonordefrin
Levonordefrin
also known as
(-)-cobefrin · BA 2818 · Corbadrina · Corbadrine · L-.alpha.-methylnoradrenaline · L-nordefrin · L-norephedrine, 3,4-dihydroxy- · Levonordefrin HCl · +3 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | RAVOCAINE AND NOVOCAIN W/ NEO-COBEFRIN | — | 1952-09-19 | fda.gov ↗ |
Trials 1
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase not applicable1 trial | ||||||
| — | NCT05875519 | May → Nov 2023 | diabetes mellitus | Minia University | Completed | No outcome recorded |
| Comparator or background therapy4 trials | ||||||
| Phase 2 | NCT07798258 Comparator | Oct 2025 → Jan 2027 expected | temporomandibular joint disorder | Cairo University | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04477317 Comparator | Aug → Sep 2021 | — | Cairo University | Completed | No outcome recorded |
| — | NCT04561921 Comparator | Oct 2020 → Oct 2021 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT02603198 Comparator | Aug 2014 → Jun 2015 | — | University of Sao Paulo | Unknown | No outcome recorded |
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Levonordefrin | “The solution will be mixed with 0.2 mL of local anaesthetic solution containing 2% mepivacaine hydrochloride with 1:20,000 levonordefrin.” NCT07798258 ↗ |
| Known as | (-)-cobefrin | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | BA 2818 | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | Corbadrina | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | Corbadrine | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | L-.alpha.-methylnoradrenaline | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | L-nordefrin | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | L-norephedrine, 3,4-dihydroxy- | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | Levonordefrin HCl | “.06mg Levonordefrin HCl during inferior alveolar nerve block” NCT04561921 ↗ |
| Known as | Neo-cobefrin | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | Nordefrin (-)-form | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Known as | NSC-757084 | ChEMBL registry synonym — accepted as the source's own label CHEMBL677 ↗ |
| Modality | Small molecule | — CHEMBL677 ↗ |
| Route | Other | “inferior alveolar nerve block” NCT04561921 ↗ |