Drugs / DS-3201b
last change Oct 2024 re-read 3 minutes ago

DS-3201b

targets EZH1, EZH2 via inhibition

Developed for
acute lymphoblastic leukemia · acute myeloid leukemia · non-Hodgkin lymphoma · small cell lung carcinoma
Investigated by
Daiichi Sankyo · Memorial Sloan Kettering Cancer Center

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT04276662 Nov 2019 → Feb 2021 — Daiichi Sankyo Completed No outcome recorded
Phase 1 NCT03110354 Apr 2017 → Mar 2021 acute lymphoblastic leukemia, acute myeloid leukemia Daiichi Sankyo Terminated No outcome recorded Stop: Enrollment
Phase 1 NCT02732275 Mar 2016 → Dec 2022 overdue non-Hodgkin lymphoma Daiichi Sankyo Active not recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03879798 Mar 2019 → May 2023 small cell lung carcinoma Memorial Sloan Kettering Cancer Center Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as DS-3201b ClinicalTrials.gov intervention name — accepted as the source's own label NCT04276662 ↗
3

NCT02732275 ↗

NCT03879798 ↗

NCT03110354 ↗

Action Inhibit “a novel inhibitor of EZH2 and EZH1” PMID 39486432 ↗ Oct 2024
Route Oral “DS-3201b administered orally to participants with AML or ALL.” NCT03110354 ↗
Target EZH1 “a novel inhibitor of EZH2 and EZH1” PMID 39486432 ↗ Oct 2024
Target EZH2 “a novel inhibitor of EZH2 and EZH1” PMID 39486432 ↗ Oct 2024