RD06-05

also known as RD06-05 CART Cell Injection

Developed for: systemic lupus erythematosus · systemic sclerosis · anti-neutrophil cytoplasmic antibody-associated vasculitis · idiopathic inflammatory myopathy · multiple sclerosis · anti-glomerular basement membrane disease · anti-neutrophil antibody associated vasculitis · autoimmune encephalitis
+12 more
· autoimmune thrombocytopenic purpura · Crohn disease · Evans syndrome · Graves disease · idiopathic multidrug-resistant nephrotic syndrome · IgA glomerulonephritis · myasthenia gravis · neuromyelitis optica · pauci-immune glomerulonephritis with ANCA · polyneuropathy, inflammatory demyelinating, chronic · Sjogren syndrome · ulcerative colitis
Investigated by: Nanjing Bioheng Biotech Co., Ltd. · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Shanghai Zhongshan Hospital · The Children's Hospital of Zhejiang University School of Medicine · Tongji Hospital

Trials 8 · a red edge is where a trial was stopped

today NCT07596680 · Ph 0 NCT07674147 · Ph 0 NCT07441525 · Ph 0 NCT07309744 · Ph 0 NCT07261345 · Ph 0 NCT07337785 · Ph 0 NCT07203404 · Ph 0 NCT06775912 · Ph 0

20252026202720282029

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 0	NCT07596680	Sep 2026 → Apr 2028 expected	Sjogren syndrome, anti-neutrophil antibody associated vasculitis, idiopathic inflammatory myopathy, systemic lupus erythematosus +1	Nanjing Bioheng Biotech Co., Ltd.	Not yet recruiting	No outcome recorded
Phase 0	NCT07674147	Jul 2026 → Jul 2029 expected	IgA glomerulonephritis, idiopathic inflammatory myopathy, idiopathic multidrug-resistant nephrotic syndrome, systemic lupus erythematosus +1	The Children's Hospital of Zhejiang University School of Medicine	Not yet recruiting	No outcome recorded
Phase 0	NCT07441525	Feb 2026 → Jan 2029 expected	Evans syndrome, autoimmune thrombocytopenic purpura	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Recruiting	No outcome recorded
Phase 0	NCT07309744	Dec 2025 → Dec 2027 expected	Crohn disease, ulcerative colitis	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Not yet recruiting	No outcome recorded
Phase 0	NCT07261345	Dec 2025 → Dec 2027 expected	Graves disease	Shanghai Zhongshan Hospital	Recruiting	No outcome recorded
Phase 0	NCT07337785	Dec 2025 → Dec 2026 expected	autoimmune encephalitis, multiple sclerosis, myasthenia gravis, polyneuropathy, inflammatory demyelinating, chronic	Tongji Hospital	Recruiting	No outcome recorded
Phase 0	NCT07203404	Jul 2025 → Jul 2027 expected	anti-glomerular basement membrane disease, anti-neutrophil cytoplasmic antibody-associated vasculitis, pauci-immune glomerulonephritis with ANCA, systemic lupus erythematosus +1	Nanjing Bioheng Biotech Co., Ltd.	Recruiting	No outcome recorded
Phase 0	NCT06775912	Jan 2025 → Jan 2027 expected	anti-neutrophil cytoplasmic antibody-associated vasculitis, multiple sclerosis, neuromyelitis optica, systemic lupus erythematosus +1	Nanjing Bioheng Biotech Co., Ltd.	Recruiting	No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

Field	Value	Cited text
Known as	RD06-05	“This is a single-arm, open-label, investigator-initiated trial (IIT) designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy...” NCT07441525 ↗ 8 “single intravenous infusion of CD19/BCMA-targeted CAR-T cells (RD06-05) at dose of 1 × 10\^7 CAR+ T cells/kg” NCT07337785 ↗ “Participants will receive a single infusion of allogenic anti-CD19/BCMA CAR-T (RD06-05).” NCT07261345 ↗ “RD06-05” NCT07337785 ↗ NCT07309744 ↗ NCT07596680 ↗ NCT07203404 ↗ NCT07674147 ↗ NCT06775912 ↗
Known as	RD06-05 CART Cell Injection	“Drug: RD06-05 CART Cell Injection” NCT07203404 ↗
Modality	Cell therapy	“Targeted CD19/BCMA CAR-T Therapy” NCT06775912 ↗
Route	Intravenous	“administered intravenously” NCT06775912 ↗
Target	CD19	“Targeted CD19/BCMA CAR-T Therapy” NCT06775912 ↗