drugset
Drugs / PAC-14028
last change Nov 2018 re-read 2 minutes ago

PAC-14028

also known as Asivatrep · PAC-14028 cream

targets TRPV1 via inhibition

Developed for
atopic eczema · rosacea · seborrheic dermatitis
Investigated by
Amorepacific Corporation · Seoul National University Hospital

Trials 12 · a red edge is where a trial was stopped

today NCT02965118 · Ph 3 NCT02748993 · Ph 1/2 NCT02757729 · Ph 2 NCT02309008 · Ph 1 NCT02565134 · Ph 2 NCT02583009 · Ph 2 NCT02749383 · Ph 2 NCT02583022 · Ph 2 NCT02052999 · Ph 2 NCT02052531 · Ph 2 NCT01638117 · Ph 1 NCT01264224 · Ph 1
20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT02309008 Nov 2014 → Apr 2016 — Amorepacific Corporation Completed No outcome recorded
Phase 1 NCT01638117 Apr → Aug 2012 — Amorepacific Corporation Completed No outcome recorded
Phase 1 NCT01264224 Dec 2010 → Jun 2012 — Amorepacific Corporation Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02748993 Mar 2016 → Sep 2018 atopic eczema Amorepacific Corporation Completed No outcome recorded
Phase 27 trials
Phase 2 NCT02757729 Oct 2015 → Aug 2016 atopic eczema Amorepacific Corporation Completed No outcome recorded
Phase 2 NCT02565134 Oct 2014 → Jun 2016 — Amorepacific Corporation Completed No outcome recorded
Phase 2 NCT02583009 Oct 2014 → Aug 2016 rosacea Amorepacific Corporation Completed No outcome recorded
Phase 2 NCT02749383 Feb → Dec 2014 seborrheic dermatitis Amorepacific Corporation Completed No outcome recorded
Phase 2 NCT02583022 Jun 2013 → Jan 2014 atopic eczema Amorepacific Corporation Completed No outcome recorded
Phase 2 NCT02052999 Feb → Jun 2013 rosacea Amorepacific Corporation Completed No outcome recorded
Phase 2 NCT02052531 Jan → Jun 2013 — Amorepacific Corporation Completed No outcome recorded
Phase 31 trial
Phase 3 NCT02965118 Nov 2016 → Nov 2018 atopic eczema Amorepacific Corporation Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as PAC-14028 “Cumulative Irritation Test of PAC-14028 in Healthy Volunteers” NCT01638117 ↗
11

NCT02965118 ↗

NCT02565134 ↗

NCT02583009 ↗

NCT02583022 ↗

NCT02757729 ↗

NCT02748993 ↗

NCT02749383 ↗

NCT01264224 ↗

NCT02052999 ↗

NCT02052531 ↗

NCT02309008 ↗
Known as Asivatrep ChEMBL registry synonym — accepted as the source's own label CHEMBL3707398 ↗
Known as PAC-14028 cream “PAC-14028 cream 0.1%” NCT02757729 ↗
Action Inhibit “TRPV1 Antagonist” NCT02965118 ↗
Route Oral “tablets, oral administration” NCT01264224 ↗
Target TRPV1 “TRPV1 Antagonist” NCT02965118 ↗