Drugs / Brenetafusp
last change Jun 2024 re-read 2 minutes ago

Brenetafusp

also known as IMC-F106C

Protein / enzyme biologic

Developed for
cancer · melanoma · myxoid liposarcoma · synovial sarcoma
Investigated by
Immunocore Ltd · National Cancer Institute (NCI)

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT04262466 Feb 2020 → Oct 2026 expected cancer Immunocore Ltd Active not recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07686367 Sep 2026 → Nov 2027 expected myxoid liposarcoma, synovial sarcoma National Cancer Institute (NCI) Not yet recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT06112314 Jun 2024 → Oct 2027 expected melanoma Immunocore Ltd Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as brenetafusp “This phase II trial studies how well brenetafusp (IMC-F106C) works in treating patients with preferentially expressed antigen of melanoma (PRAME) positive synovial sarcoma and...” NCT07686367
2

NCT04262466

NCT06112314

Known as IMC-F106C “Brenetafusp (IMC-F106C) is an immune-mobilizing monoclonal T cell receptor against cancer (ImmTAC ®) designed for the treatment of cancers positive for the tumor-associated...” NCT04262466
Modality Protein / enzyme biologic “Brenetafusp (IMC-F106C) is an immune-mobilizing monoclonal T cell receptor against cancer (ImmTAC ®)” NCT04262466
Route Intravenous “Brenetafusp IV infusions” NCT04262466