Drugs / TGRX-326
last change Apr 2026 re-read 2 minutes ago

TGRX-326

targets ALK via inhibition

Developed for
non-small cell lung carcinoma
Investigated by
Shenzhen TargetRx Co., Ltd. · Sun Yat-sen University Cancer Center · The First Affiliated Hospital of Bengbu Medical University · Affiliated Cancer Hospital of Guizhou Medical University · Bingzhou Medical University Affiliated Hospital · Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center
+32 more · Capital Medical School Beijing Chest Hospital · First Affiliated Hospital Xi'an Jiaotong University · First Affiliated Hospital, Sun Yat-Sen University · First Hospital of China Medical University · Fujian Cancer Hospital · Haerbin Medical University Cancer Hospital · Henan Cancer Hospital · Hunan Cancer Hospital · Jiangxi Provincial Cancer Hospital · Jilin Provincial Tumor Hospital · Jingzhou First People's Hospital · Liaoning Cancer Hospital & Institute · Mianyang Central Hospital · Nanchang University First Affiliated Hospital · Ningbo No. 1 Hospital · Shandong Cancer Hospital and Institute · Shanghai Chest Hospital · Shijiazhuang People's Hospital · Sichuan Cancer Hospital and Research Institute · The Affiliated Hospital of Qingdao University · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · The First Affiliated Hospital of Soochow University · The First Affiliated Hospital of Zhengzhou University · The Second Affiliated Hospital of AFMU · Tianjin Cancer Hospital · Tongji Hospital · West China Hospital · Xiangyang Central Hospital · Xinxiang Central Hospital · Yunnan Cancer Hospital · Zhejiang Cancer Hospital · Zhejiang University

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT06438367 Jun → Jul 2024 non-small cell lung carcinoma Shenzhen TargetRx Co., Ltd. Completed No outcome recorded
Phase 1 NCT06294561 Mar → May 2024 non-small cell lung carcinoma Shenzhen TargetRx Co., Ltd. Completed No outcome recorded
Phase 1 NCT06304805 Dec 2023 → Jan 2024 non-small cell lung carcinoma Shenzhen TargetRx Co., Ltd. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05955391 Jan 2023 → Dec 2024 overdue non-small cell lung carcinoma Shenzhen TargetRx Co., Ltd. Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT06082635 Dec 2023 → Apr 2026 overdue non-small cell lung carcinoma Shenzhen TargetRx Co., Ltd. Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as TGRX-326 “A study evaluating the effects of food intake on the pharmacokinetic (PK) profiles of TGRX-326 and the effect of different drug specifications on human bioavailability for...” NCT06304805
4

NCT06082635

NCT06438367

NCT05955391

NCT06294561

Action Inhibit “TGRX-326, an ALK inhibitor” NCT06294561
Route Oral “TGRX-326 60 mg orally on Day 1” NCT06294561
Target ALK “TGRX-326, an ALK inhibitor” NCT06294561