Drugs / Lifastuzumab vedotin
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT01995188 | Dec 2013 → Nov 2016 | non-small cell lung carcinoma | Genentech, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01363947 | Jun 2011 → Jun 2016 | non-small cell lung carcinoma | Genentech, Inc. | Completed | No outcome recorded |
| Phase 21 trial · 1 missed | ||||||
| Phase 2 | NCT01991210 | Feb 2014 → Aug 2016 | ovarian cancer | Genentech, Inc. | Terminated | Missed primary |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Lifastuzumab vedotin | “Lifastuzumab vedotin (LIFA) is a humanized anti-NaPi2b monoclonal antibody conjugated to a potent antimitotic agent, monomethyl auristatin E, which inhibits cell division by...” PMID 29401246 ↗ Apr 2018 |
| Known as | DNIB0600A | “Anti-NaPi2b antibody-drug conjugate lifastuzumab vedotin (DNIB0600A) compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer in a...” PMID 29401246 ↗ Apr 2018 |
| Known as | Lifastuzumab vedotina | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297938 ↗ |
| Known as | Lifastuzumab vedotine | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297938 ↗ |
| Known as | NAPI3B | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297938 ↗ |
| Known as | RG-7599 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297938 ↗ |
| Modality | Monoclonal antibody | “Lifastuzumab vedotin (LIFA) is a humanized anti-NaPi2b monoclonal antibody conjugated to a potent antimitotic agent, monomethyl auristatin E, which inhibits cell division by...” PMID 29401246 ↗ Apr 2018 |
| Route | Intravenous | “administered via IV infusion” NCT01363947 ↗ |
| Target | SLC34A2 | “Sodium-dependent phosphate transport protein 2B binding agent” CHEMBL4297938 ↗ |