Drugs / Aza-TdC
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Aza-TdC

Small molecule targets DNMT1 via inhibition

Developed for
neoplasm
Investigated by
National Cancer Institute (NCI)

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03366116 Nov 2018 → Sep 2026 overdue neoplasm National Cancer Institute (NCI) Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Aza-TdC ClinicalTrials.gov intervention name — accepted as the source's own label NCT03366116 ↗
Known as 5-aza-4'-thio-2'- deoxycytidine “The nucleoside analog 5-aza-4'-thio-2'- deoxycytidine (Aza-TdC) is incorporated into DNA” NCT03366116 ↗
Action Inhibit “Treatment with Aza-TdC is anticipated to yield inhibition of tumor growth due to DNMT1 depletion” NCT03366116 ↗
Modality Small molecule “The nucleoside analog” NCT03366116 ↗
Route Oral “Aza-TdC will be administered orally once a day” NCT03366116 ↗
Target DNMT1 “due to DNMT1 depletion” NCT03366116 ↗