Drugs / 4SCAR T cells
last change Jun 2026 re-read 3 minutes ago

4SCAR T cells

Cell therapy targets CD19 via depletion

Developed for
autoimmune disease
Investigated by
Shenzhen Geno-Immune Medical Institute

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05459870 Jun 2026 → Dec 2029 expected autoimmune disease Shenzhen Geno-Immune Medical Institute Recruiting No outcome recorded
Phase 1/2 NCT06435897 May 2024 → Jul 2027 expected autoimmune disease Shenzhen Geno-Immune Medical Institute Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 4SCAR-T cells “clinical evidence to support the use of 4SCAR-T cells and MSCs in the treatment of autoimmune diseases.” NCT06435897 ↗
2

NCT06435897 ↗

NCT05459870 ↗

Action Deplete “The activated CAR-T cells can target and kill B cells.” NCT05459870 ↗
Modality Cell therapy “CAR-T cell technology” NCT05459870 ↗
Route Intravenous “via IV” NCT05459870 ↗
Target CD19 “Besides targeting CD19, specific CARs targeting other B cell surface molecules including BCMA, CD138, and BAFF-R will also be included in the treatment regimen.” NCT05459870 ↗