Drugs / NKG2D-based CAR T-cells
last change Dec 2023 re-read 3 minutes ago

NKG2D-based CAR T-cells

Cell therapy

Developed for
colon carcinoma · glioblastoma · hepatocellular carcinoma · medulloblastoma
Investigated by
KAEDI · Fudan University · Jiujiang University Affiliated Hospital

Trials 2

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05131763 Mar 2021 → Dec 2022 colon carcinoma, glioblastoma, hepatocellular carcinoma, medulloblastoma Fudan University Unknown No outcome recorded
Phase 1 NCT04270461 Mar → Oct 2020 colon carcinoma, glioblastoma, hepatocellular carcinoma, medulloblastoma Jiujiang University Affiliated Hospital Withdrawn No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as NKG2D-based CAR T-cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04270461 ↗
1

NCT05131763 ↗

Action Deplete “NKG2D-based CAR-T cells showed strong cytotoxicity against NKG2DL+ cell lines in vitro” NCT04270461 ↗
Modality Cell therapy “NKG2D-based CAR-T represent a potentially effective and safety therapeutic approach” NCT04270461 ↗
Route Intravenous “administered by i.v.” NCT04270461 ↗