Drugs / BNT324
last change Apr 2026 re-read 2 minutes ago

BNT324

also known as DB-1311

Other / unclassified

Developed for
cancer · lung cancer · prostate carcinoma
Investigated by
BioNTech SE · DualityBio Inc. · BioNTech (Shanghai) Pharmaceuticals Co., Ltd.

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/22 trials
Phase 1/2 NCT06892548 May 2025 → Sep 2028 expected lung cancer BioNTech SE Recruiting No outcome recorded
Phase 1/2 NCT05914116 Aug 2023 → Dec 2027 expected cancer DualityBio Inc. Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT06953089 Jul 2025 → Jun 2030 expected cancer DualityBio Inc. Recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07365995 Apr 2026 → Feb 2031 expected prostate carcinoma BioNTech SE Recruiting No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2024-06-24 BioNTech SE BioNTech and DualityBio Receive FDA Fast Track Designation for Antibody-Drug Conjugate Candidate BNT324/DB-1311 in Prostate Cancer biontech.com

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as BNT324 “A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors” NCT05914116
3

“DB-1311/BNT324NCT06953089

NCT06892548

NCT07365995

Known as DB-1311 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05914116
1

NCT06953089

Modality Other / unclassified “BNT324, a B7-H3 antibody-drug conjugate (ADC)” NCT06892548
Route Intravenous “Administered I.V.(intravenous infusion)” NCT05914116