Drugs / ZN-d5
last change Jul 2024 re-read 2 minutes ago

ZN-d5

Developed for
acute myeloid leukemia · non-Hodgkin lymphoma · AL amyloidosis
Investigated by
Zentalis Pharmaceuticals, Inc. · Zentera Therapeutics HK Limited

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT05127811 Oct 2021 → May 2023 non-Hodgkin lymphoma Zentera Therapeutics HK Limited Terminated No outcome recorded
Phase 1 NCT04854174 Jun 2021 Zentalis Pharmaceuticals, Inc. Completed No outcome recorded
Phase 1 NCT04500587 Oct 2020 → Dec 2023 acute myeloid leukemia, non-Hodgkin lymphoma Zentalis Pharmaceuticals, Inc. Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT05682170 Dec 2022 → Jul 2024 acute myeloid leukemia Zentalis Pharmaceuticals, Inc. Terminated No outcome recorded
Phase 1/2 NCT05199337 Nov 2021 → Feb 2024 AL amyloidosis Zentalis Pharmaceuticals, Inc. Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as ZN-d5 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05199337
4

NCT04500587

NCT05127811

NCT05682170

NCT04854174

Action Inhibit “the novel BCL-2 inhibitor ZN-d5” NCT04500587
Route Oral Oral agent; 25 mg or 100 mg formulation” NCT04500587