Drugs / Anti-CD19-CAR CMV-specific T-lymphocytes
last change Dec 2025 re-read 2 minutes ago

Anti-CD19-CAR CMV-specific T-lymphocytes

Cell therapy targets CD19

Developed for
acute lymphoblastic leukemia · diffuse large B-cell lymphoma · high grade B-cell lymphoma · mantle cell lymphoma
Investigated by
City of Hope Medical Center · National Cancer Institute (NCI)

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT06735690 Dec 2025 → Mar 2029 expected acute lymphoblastic leukemia City of Hope Medical Center Recruiting No outcome recorded
Phase 12 trials
Phase 1 NCT05801913 Sep 2023 → Mar 2028 expected high grade B-cell lymphoma City of Hope Medical Center Recruiting No outcome recorded
Phase 1 NCT05432635 Aug 2023 → Mar 2028 expected diffuse large B-cell lymphoma, mantle cell lymphoma City of Hope Medical Center Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Anti-CD19-CAR CMV-specific T-lymphocytes ClinicalTrials.gov intervention name — accepted as the source's own label NCT05801913
2

NCT05432635

NCT06735690

Action Deplete “CAR T-cells are a type of treatment in which a patient's T-cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells.” NCT05432635
Modality Cell therapy “CAR T-cells are a type of treatment in which a patient's T-cells (a type of immune system cell) are changed in the laboratory” NCT05432635
Route Intravenous “Given IV” NCT05432635
Target CD19 “Anti-CD19-CAR CMV-specific T-lymphocytes” NCT05432635