Drugs / Efungumab
last change Nov 2007 re-read 2 minutes ago

Efungumab

Monoclonal antibody

Developed for
Cryptococcal meningitis · breast cancer
Investigated by
Novartis Pharmaceuticals · NeuTec Pharma

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Refused (EMA) EU (EMA) Mycograb 2007-05-22 europa.eu

Trials 3 · a red edge is where a trial was stopped

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00217815 Sep 2005 → Oct 2006 breast cancer NeuTec Pharma Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00324025 Mar → Sep 2007 Cryptococcal meningitis Novartis Pharmaceuticals Terminated No outcome recorded
Phase 2 NCT00847678 Aug 2006 → Nov 2007 Cryptococcal meningitis Novartis Pharmaceuticals Terminated No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Efungumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT00847678
Known as HSP-90MAB ChEMBL registry synonym — accepted as the source's own label CHEMBL1743009
Known as MYC-123 ChEMBL registry synonym — accepted as the source's own label CHEMBL1743009
Known as MYC-123A ChEMBL registry synonym — accepted as the source's own label CHEMBL1743009
Known as MYC-123A MYC-123B MYC-124 HSP90MAB ChEMBL registry synonym — accepted as the source's own label CHEMBL1743009
Known as MYC-123B ChEMBL registry synonym — accepted as the source's own label CHEMBL1743009
Known as MYC-124 ChEMBL registry synonym — accepted as the source's own label CHEMBL1743009
Known as Mycograb “Biological: Efungumab (Mycograb)” NCT00847678
2

NCT00324025

NCT00217815

Action Inhibit “Mycograb® binds to hsp90, inhibiting hsp90 chaperone functioning” NCT00217815
Modality Monoclonal antibody CHEMBL1743009
Route Intravenous “Mycograb Administered IV” NCT00217815