Drugs / Romiplostim N01
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Romiplostim N01

Peptide targets MPL via activation

Developed for
thrombocytopenia · aplastic anemia · autoimmune thrombocytopenia · cancer · disease related to hematopoietic stem cell transplant · acute myeloid leukemia · idiopathic aplastic anemia · myelodysplastic syndrome
Investigated by
Institute of Hematology & Blood Diseases Hospital, China · Peking Union Medical College Hospital · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Qilu Pharmaceutical Co., Ltd. · Tianjin Medical University Cancer Institute and Hospital · Affiliated Hospital of Nantong University
+33 more · Changzhi Medical College · China-Japan Union Hospital, Sun Yat-sen University Cancer Center · Hebei Medical University Fourth Hospital · Henan Provincial People's Hospital · North China University of Science and Technology · Peking University Cancer Hospital and Institute · Peking University International Hospital · Peking University People's Hospital · Shanxi Province Cancer Hospital · Shenzhen Second People's Hospital · The Affiliated Hospital of Qingdao University · The First Affiliated Hospital of Bengbu Medical University · The First Affiliated Hospital of Soochow University · The Second Affiliated Hospital of Dalian Medical University · The Second Affiliated Hospital of Kunming Medical University · Weifang People's Hospital · Affiliated Hospital of North Sichuan Medical College · Baoding First Central Hospital · First Affiliated Hospital of Zhejiang University · Guizhou Provincial People's Hospital · Henan Cancer Hospital · Jun Wang · Qilu Hospital of Shandong University · Shandong University · Suining Central Hospital · The First Affiliated Hospital of Henan University of Science and Technology · The First People's Hospital of Yunnan · Tianjin Hospital of ITCWM-Nankai Hospital · Tianjin Medical University Second Hospital · Tianjin People's Hospital · Tianjin Third Central Hospital · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Zhujiang Hospital

Trials 20

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07321626 Jun 2025 → Dec 2027 expected acute myeloid leukemia, disease related to hematopoietic stem cell transplant, myelodysplastic syndrome First Affiliated Hospital of Zhejiang University Recruiting No outcome recorded
Phase 215 trials
Phase 2 NCT07829952 Nov 2026 → Jun 2028 expected disease related to hematopoietic stem cell transplant, thrombocytopenia The First Affiliated Hospital of Henan University of Science and Technology Not yet recruiting No outcome recorded
Phase 2 NCT07532408 Jun 2026 → Dec 2028 aplastic anemia Peking Union Medical College Hospital Withdrawn No outcome recorded
Phase 2 NCT07523009 Jun 2026 → Dec 2028 aplastic anemia Peking Union Medical College Hospital Withdrawn No outcome recorded
Phase 2 NCT07400250 Apr → Oct 2026 expected autoimmune thrombocytopenia Peking Union Medical College Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07558434 Apr 2026 → Dec 2028 expected aplastic anemia Peking Union Medical College Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07572084 Apr 2026 → Dec 2028 expected aplastic anemia Peking Union Medical College Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07043894 Dec 2025 → Sep 2026 overdue cancer, hematopoietic and lymphoid cell neoplasm, thrombocytopenia Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting No outcome recorded
Phase 2 NCT07586813 Dec 2025 → Oct 2027 expected colorectal cancer, malignant pancreatic neoplasm, thrombocytopenia Peking University People's Hospital Recruiting No outcome recorded
Phase 2 NCT07586826 Dec 2025 → Oct 2027 expected breast cancer, cervical cancer, fallopian tube cancer, non-small cell lung carcinoma +3 Peking University People's Hospital Recruiting No outcome recorded
Phase 2 NCT07128576 Sep 2025 → Aug 2027 expected cancer Zhujiang Hospital Not yet recruiting No outcome recorded
Phase 32 trials
Phase 3 NCT07345000 Jan 2026 → Oct 2029 expected idiopathic aplastic anemia Qilu Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT06440824 Jun 2024 → Jun 2025 thrombocytopenia Shandong University Unknown No outcome recorded
Phase not applicable2 trials
— NCT07206823 Sep 2025 → Feb 2027 expected autoimmune thrombocytopenia The First Affiliated Hospital of Soochow University Recruiting No outcome recorded
— NCT07185893 Sep 2025 → Mar 2028 expected cancer, thrombocytopenia Jun Wang Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 20 sources stand behind the page.

FieldValueCited text
Known as Romiplostim N01 “Romiplostim N01, starting dose of 1 µg/kg, subcutaneous injection, given on the third day of IVIG, once a week, for up to one month.” NCT06686927 ↗
19

NCT07321626 ↗

NCT06658834 ↗

NCT06440824 ↗

NCT07532408 ↗

NCT07523009 ↗

NCT07586826 ↗

NCT07586813 ↗

NCT07043894 ↗

NCT07206823 ↗

NCT07063225 ↗

Show 9 more sources

Action Activate “activate them” NCT06613880 ↗
Modality Peptide “Its TPO peptide can bind to TPO receptors on megakaryocyte precursors in the bone marrow” NCT06613880 ↗
Route Subcutaneous “subcutaneous injection” NCT06440824 ↗
Target MPL “both romiplostim and eltrombopag/hyrtiopeg activate the TPO receptor (c-Mpl)” NCT07523009 ↗