Drugs / ceperognastat
last change Jul 2026 re-read 3 minutes ago

ceperognastat

also known as LY3372689

Small molecule

Developed for
Alzheimer disease
Investigated by
Eli Lilly and Company

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT05749848 Feb → Apr 2023 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT04392271 Aug → Oct 2020 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT04106206 Oct 2019 → Feb 2020 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT03944031 May 2019 → Feb 2020 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT03819270 Feb → Jun 2019 — Eli Lilly and Company Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT05063539 Sep 2021 → Jul 2024 Alzheimer disease Eli Lilly and Company Completed Missed primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as ceperognastat “To evaluate the efficacy and safety of the potent oral OGA inhibitor ceperognastat in early symptomatic Alzheimer disease (AD).” PMID 42441396 ↗ Jul 2026
Known as LY3372689 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03819270 ↗
4

NCT03944031 ↗

NCT04392271 ↗

NCT04106206 ↗

NCT05749848 ↗

Modality Small molecule — CHEMBL5095251 ↗
Route Oral “Escalating doses of LY3372689 administered orally in healthy participants in two of three study periods” NCT03819270 ↗