Drugs / REGN7999
last change Sep 2024 re-read 3 minutes ago

REGN7999

targets TMPRSS6 via inhibition

Developed for
beta-thalassemia intermedia
Investigated by
Regeneron Pharmaceuticals

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05481333 Oct 2022 → Aug 2023 — Regeneron Pharmaceuticals Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06421636 Sep 2024 → Dec 2026 expected beta-thalassemia intermedia Regeneron Pharmaceuticals Active not recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2023-11-03 Regeneron Pharmaceuticals Results Regeneron to Highlight Scientific Advancements Across Diversified Pipeline in Difficult-to-Treat Blood Cancers and Disorders at ASH regeneron.com ↗
Single Ascending Doses of REGN7999, A Monoclonal Antibody Inhibitor of TMPRSS6, Increase Serum Hepcidin And Cause Deep, Sustained Reductions in Serum Iron in Healthy Human Volunteers

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as REGN7999 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06421636 ↗
1

NCT05481333 ↗

Action Inhibit “an inhibitor of TMPRSS6” NCT06421636 ↗
Route Intravenous “single ascending intravenous (IV) and subcutaneous (SC) doses of REGN7999” NCT05481333 ↗
Route Subcutaneous “single ascending intravenous (IV) and subcutaneous (SC) doses of REGN7999” NCT05481333 ↗
Target TMPRSS6 “an inhibitor of TMPRSS6” NCT06421636 ↗