Drugs / MSC303
last change May 2026 re-read 3 minutes ago

MSC303

targets MS4A1 via depletion

Developed for
lupus nephritis · pauci-immune glomerulonephritis with ANCA
Investigated by
Shanghai Changzheng Hospital

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT07000292 Jun 2025 → May 2026 overdue lupus nephritis, pauci-immune glomerulonephritis with ANCA Shanghai Changzheng Hospital Not yet recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as MSC303 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07000292 ↗
Action Deplete “MSC303 recruits activated T cells around B cells, thereby enhancing the killing effect on B cells.” NCT07000292 ↗
Route Subcutaneous “Subcutaneous Injection of MSC303” NCT07000292 ↗
Target CD20 “targeting both CD20 and CD3” NCT07000292 ↗