Drugs / Patient Derived CD171 specific CAR T cells expressing EGFRt (2nd generation T cells)
last change Nov 2023 re-read 3 minutes ago

Patient Derived CD171 specific CAR T cells expressing EGFRt (2nd generation T cells)

Developed for
ganglioneuroblastoma · neuroblastoma
Investigated by
Ben Towne Center for Childhood Cancer Research · Seattle Children's Hospital · The Evan Foundation

Trials 1

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02311621 Nov 2014 → Nov 2023 overdue ganglioneuroblastoma, neuroblastoma Seattle Children's Hospital Active not recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Patient Derived CD171 specific CAR T cells expressing EGFRt (2nd generation T cells) ClinicalTrials.gov intervention name — accepted as the source's own label NCT02311621 ↗
Action Deplete “The CAR enables the T cell to recognize and kill the neuroblastoma cell through the recognition of CD171” NCT02311621 ↗
Route Intravenous “Intravenous infusion of autologous T cells transduced to express 4-1BB:zeta CD171CAR and EGFRt (2nd generation T cells)” NCT02311621 ↗