Drugs / Quemliclustat

Trials 12 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07364214 Feb → Apr 2026 Arcus Biosciences, Inc. Completed No outcome recorded
Phase 1 NCT04104672 Nov 2019 → May 2027 expected malignant exocrine pancreas neoplasm Arcus Biosciences, Inc. Active not recruiting No outcome recorded
Phase 1/24 trials
Phase 1/2 NCT07667335 Dec 2026 → Jul 2029 expected infiltrating urothelial carcinoma, urinary bladder carcinoma, urothelial carcinoma Fred Hutchinson Cancer Center Not yet recruiting No outcome recorded
Phase 1/2 NCT05688215 Mar 2023 → Dec 2026 expected pancreatic ductal adenocarcinoma Jonsson Comprehensive Cancer Center Recruiting No outcome recorded
Phase 1/2 NCT04660812 May 2021 → Sep 2025 colorectal cancer Arcus Biosciences, Inc. Completed No outcome recorded
Phase 1/2 NCT04381832 Jul 2020 → Aug 2024 castration-resistant prostate carcinoma Arcus Biosciences, Inc. Completed No outcome recorded
Phase 25 trials
Phase 2 NCT06048484 May 2024 → Apr 2027 expected pancreatic ductal adenocarcinoma Gulam Manji Recruiting No outcome recorded
Phase 2 NCT06048133 Mar 2024 → Jul 2026 overdue cholangiocarcinoma Nataliya Uboha Active not recruiting No outcome recorded
Phase 2 NCT05915442 Jul 2023 → Dec 2026 expected metastatic prostate carcinoma Catherine Spina Recruiting No outcome recorded
Phase 2 NCT05676931 Feb 2023 → Dec 2027 expected non-small cell lung carcinoma Gilead Sciences Active not recruiting No outcome recorded
Phase 2 NCT05329766 Jun 2022 → Jan 2027 expected digestive system cancer Arcus Biosciences, Inc. Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT06608927 Dec 2024 → Nov 2030 expected pancreatic ductal adenocarcinoma Arcus Biosciences, Inc. Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04575311 Comparator Oct 2020 → Sep 2021 Arcus Biosciences, Inc. Completed No outcome recorded
Phase 1 NCT03677973 Comparator Oct 2018 → Aug 2019 Arcus Biosciences, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 15 sources stand behind the page.

FieldValueCited text
Known as Quemliclustat ClinicalTrials.gov intervention name — accepted as the source's own label NCT05688215
9

NCT04381832

NCT06608927

NCT05915442

NCT06048133

NCT05676931

NCT07364214

NCT06048484

NCT05329766

NCT07667335

Known as AB680 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04575311
3

NCT04104672

NCT04660812

NCT03677973

Known as COMPOUND 55 ChEMBL registry synonym — accepted as the source's own label CHEMBL4471306
Action Inhibit “AB680 is a Cluster of Differentiation (CD)73 Inhibitor” NCT03677973
Modality Small molecule CHEMBL4471306
Route Intravenous “AB680 will be administered as single and multiple intravenous doses” NCT03677973