Drugs / AZD9056
last change Oct 2012 re-read 9 days ago

AZD9056

Small molecule targets P2RX7 via inhibition

Developed for
rheumatoid arthritis
Investigated by
AstraZeneca

Trials 5

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT00908934 May → Jul 2009 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00920608 May → Sep 2009 rheumatoid arthritis AstraZeneca Withdrawn No outcome recorded
Phase 1 NCT00736606 Aug → Sep 2008 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00700986 Jun → Aug 2008 rheumatoid arthritis AstraZeneca Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT00520572 Aug 2007 → Mar 2009 rheumatoid arthritis AstraZeneca Completed Missed primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as AZD9056 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00908934 ↗
4

NCT00520572 ↗

NCT00920608 ↗

NCT00700986 ↗

NCT00736606 ↗

Action Inhibit “The P2X(7) purinergic receptor antagonist AZD9056” PMID 22966146 ↗ Oct 2012
1

“P2X purinoceptor 7 antagonist” CHEMBL3545108 ↗

Modality Small molecule — CHEMBL3545108 ↗
Route Oral “orally administered AZD9056” PMID 22966146 ↗ Oct 2012
Target P2RX7 “P2X purinoceptor 7 antagonist” CHEMBL3545108 ↗