Drugs / Nelitolimod

Trials 19 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT07172282 Nov 2025 → Nov 2027 expected colorectal cancer Northwell Health Recruiting No outcome recorded
Phase 110 trials
Phase 1 NCT06710223 Jan 2025 → Jun 2027 expected hepatocellular carcinoma University of California, San Diego Recruiting No outcome recorded
Phase 1 NCT05607953 Mar 2023 → Sep 2027 expected pancreatic adenocarcinoma TriSalus Life Sciences, Inc. Active not recruiting No outcome recorded
Phase 1 NCT04935229 Aug 2021 → Jul 2024 uveal melanoma TriSalus Life Sciences, Inc. Terminated No outcome recorded
Phase 1 NCT04050085 Aug 2019 → Dec 2021 pancreatic adenocarcinoma University of California, Davis Completed No outcome recorded
Phase 1 NCT03831295 Mar 2019 → Oct 2021 metastatic malignant neoplasm Ronald Levy Completed No outcome recorded
Phase 1 NCT03410901 Apr 2018 → Oct 2024 chronic lymphocytic leukemia/small lymphocytic lymphoma, lymphoplasmacytic lymphoma, mantle cell lymphoma, marginal zone lymphoma Ronald Levy Completed No outcome recorded
Phase 1 NCT02731742 Jun 2016 → Jan 2018 neoplasm Merck Sharp & Dohme LLC Terminated No outcome recorded
Phase 1 NCT01745354 Aug 2012 → Nov 2014 Hodgkins lymphoma, non-Hodgkin lymphoma Robert Lowsky Terminated No outcome recorded
Phase 1 NCT00823862 Oct 2008 → Dec 2009 chronic hepatitis C virus infection Dynavax Technologies Corporation Completed No outcome recorded
Phase 1 NCT00599001 Jan → Mar 2008 Dynavax Technologies Corporation Completed No outcome recorded
Phase 1/26 trials
Phase 1/2 NCT05220722 Mar 2022 → Jul 2024 hepatocellular carcinoma, intrahepatic cholangiocarcinoma TriSalus Life Sciences, Inc. Terminated No outcome recorded
Phase 1/2 NCT03322384 Jan 2018 → Feb 2020 cancer, lymphoma University of California, Davis Completed No outcome recorded
Phase 1/2 NCT02927964 Nov 2016 → May 2023 follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma Robert Lowsky Completed No outcome recorded
Phase 1/2 NCT02521870 Sep 2015 → Apr 2020 head and neck cancer, metastatic melanoma Dynavax Technologies Corporation Terminated No outcome recorded
Phase 1/2 NCT02266147 Oct 2014 → Apr 2017 B-cell neoplasm Dynavax Technologies Corporation Terminated No outcome recorded
Phase 1/2 NCT02254772 Sep 2014 → Nov 2016 MALT lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma, nodal marginal zone B-cell lymphoma, splenic marginal zone lymphoma Robert Lowsky Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02014376 Jan → Jun 2014 epidermolysis bullosa Scioderm, Inc. Completed No outcome recorded
Phase 2 NCT01042379 Mar 2010 → Dec 2030 expected HER2 positive breast carcinoma, angiosarcoma, female breast carcinoma, hormone receptor-positive breast cancer +1 QuantumLeap Healthcare Collaborative Recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 20 sources stand behind the page.

FieldValueCited text
Known as Nelitolimod ClinicalTrials.gov intervention name — accepted as the source's own label NCT07172282
Known as SD-101 SD-101NCT02014376
18

NCT05607953

NCT02731742

NCT04935229

NCT02014376

NCT03322384

NCT02927964

NCT00823862

NCT02266147

NCT03831295

NCT05220722

NCT02254772

NCT01745354

NCT01042379

NCT00599001

NCT06710223

NCT03410901

NCT04050085

NCT02521870

Known as SD-101 FREE ACID ChEMBL registry synonym — accepted as the source's own label CHEMBL6068457
Action Activate “TLR9 Agonist” NCT00823862
Modality Oligonucleotide (other) “CpG Class C Immunostimulatory Sequence (ISS)” NCT00823862
Route Subcutaneous “subjects will receive a single subcutaneous injection of either SD-101 or placebo (PBS)” NCT00599001
Target TLR9 TLR9 Agonist” NCT00823862