Drugs / MK0686
last change Aug 2006 re-read 3 minutes ago

MK0686

Small molecule targets BDKRB1 via inhibition

Developed for
osteoarthritis · postherpetic neuralgia
Investigated by
Merck Sharp & Dohme LLC

Trials 3

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00282763 Dec 2005 → Aug 2006 postherpetic neuralgia Merck Sharp & Dohme LLC Terminated No outcome recorded
Phase 2 NCT00296569 Sep 2005 → May 2006 osteoarthritis Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 2 NCT00533403 Jul → Nov 2004 — Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MK-0686 “This study is being conducted to assess the safety and tolerability of MK-0686 and to evaluate its efficacy in the treatment of osteoarthritis of the hip or knee in men and women.” NCT00296569 ↗
3

NCT00282763 ↗

NCT00296569 ↗

NCT00533403 ↗

Action Inhibit “Bradykinin B1 receptor antagonist” CHEMBL232943 ↗
Modality Small molecule — CHEMBL232943 ↗
Target BDKRB1 “Bradykinin B1 receptor antagonist” CHEMBL232943 ↗