Drugs / RAZPIPADON
last change Feb 2025 re-read 3 minutes ago

RAZPIPADON

also known as PF-06669571 · CVL-871 · PW-0464, (-)-

Small molecule

Developed for
Parkinson disease
Investigated by
Pfizer · AbbVie

Trials 3

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials · 1 missed
Phase 1 NCT02565628 Nov 2015 → May 2016 Parkinson disease Pfizer Completed Missed primary
Phase 1 NCT02184429 Jul 2014 → Mar 2015 — Pfizer Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04958031 Jun 2021 → Feb 2025 — AbbVie Terminated No outcome recorded Stop: Business

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2021-06-15 AbbVie Regulatory Cerevel Therapeutics Announces Fast Track Designation Granted by the U.S. FDA to CVL-871 for the Treatment of Dementia-Related Apathy abbvie.com ↗

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as RAZPIPADON ChEMBL registry synonym — accepted as the source's own label CHEMBL3697578 ↗
Known as CVL-871 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04958031 ↗
Known as PF-06669571 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02184429 ↗
1

NCT02565628 ↗

Known as PW-0464, (-)- ChEMBL registry synonym — accepted as the source's own label CHEMBL3697578 ↗
Action Activate “dopamine D1 receptor partial agonist” PMID 29478239 ↗ Jun 2018
Modality Small molecule — CHEMBL3697578 ↗
Route Oral “Oral dosing of 0.15 mg PF-06669571” NCT02184429 ↗