Drugs / PAT-1251
last change Jul 2019 re-read 3 minutes ago

PAT-1251

targets LOXL2 via inhibition

Developed for
myelofibrosis · primary myelofibrosis
Investigated by
M.D. Anderson Cancer Center · National Cancer Institute (NCI) · PharmAkea, Inc.

Trials 2

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02852551 Jul → Nov 2016 — PharmAkea, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04054245 Jul 2019 myelofibrosis, primary myelofibrosis M.D. Anderson Cancer Center Withdrawn No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as PAT-1251 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04054245 ↗
1

NCT02852551 ↗

Action Inhibit “LOXL2 inhibitor PAT-1251” NCT04054245 ↗
Route Oral “PAT-1251 orally administered to healthy subjects” NCT02852551 ↗
Target LOXL2 “LOXL2 inhibitor PAT-1251” NCT04054245 ↗