Drugs / EGFR IL12 CART
last change May 2021 re-read 3 minutes ago

EGFR IL12 CART

Cell therapy targets EGFR via depletion

Developed for
colorectal cancer
Investigated by
Shenzhen Second People's Hospital · The Pregene (ShenZhen) Biotechnology Company, Ltd.

Trials 1

201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03542799 May 2018 → May 2020 colorectal cancer Shenzhen Second People's Hospital Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as EGFR -IL12 -CART “This is a clinical study to observe the maximum tolerated dose (MTD) and the safety and feasibility of chimeric antigen receptor EGFR (EGFR -IL12 -CART) cells in metastatic...” NCT03542799 ↗
1

NCT03542799 ↗

Action Deplete “in order to tells the T cells to recognize their target tumor cells and potentially kill them” NCT03542799 ↗
Modality Cell therapy “CART cells will then be expanded in vitro and then administered to subjects.” NCT03542799 ↗
Target EGFR “This is a clinical study to observe the maximum tolerated dose (MTD) and the safety and feasibility of chimeric antigen receptor EGFR (EGFR -IL12 -CART) cells in metastatic...” NCT03542799 ↗