Drugs / OB-002
last change Aug 2025 re-read 3 minutes ago

OB-002

also known as 5p12-rantes · OB-002H

targets CCR5 via inhibition

Developed for
breast cancer · colorectal cancer · gastric cancer · malignant pancreatic neoplasm · metastatic malignant neoplasm · urothelial carcinoma
Investigated by
Orion Biotechnology · Scope International AG

Trials 2

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04791007 Oct 2019 → Apr 2020 — Orion Biotechnology Completed No outcome recorded
Phase 11 trial
Phase 1 NCT05940844 Jan 2024 → Apr 2025 breast cancer, colorectal cancer, gastric cancer, malignant pancreatic neoplasm +2 Orion Biotechnology Withdrawn No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as OB-002 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05940844 ↗
1

NCT04791007 ↗

Known as 5p12-rantes ChEMBL registry synonym — accepted as the source's own label CHEMBL5314995 ↗
Known as OB-002H “The purpose of this study was to characterize the safety, acceptability, and pharmacokinetic profile of a gel formulation of OB-002 (OB-002H).” PMID 33749321 ↗ Apr 2021
Action Inhibit “OB-002 is an extremely potent CCR5 antagonist” PMID 33749321 ↗ Apr 2021
Target CCR5 “OB-002 is an extremely potent CCR5 antagonist” PMID 33749321 ↗ Apr 2021