Drugs / CERE-120
last change Nov 2017 re-read 3 minutes ago

CERE-120

also known as AAV2-NTN

Gene therapy (AAV / viral vector)

Developed for
Parkinson disease
Investigated by
Sangamo Therapeutics · Ceregene

Trials 3

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00252850 Jun 2005 → Mar 2007 Parkinson disease Sangamo Therapeutics Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT00985517 Oct 2009 → Nov 2014 Parkinson disease Sangamo Therapeutics Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT00400634 Nov 2006 → Nov 2008 Parkinson disease Sangamo Therapeutics Completed Missed primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as CERE-120 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00400634 ↗
2

NCT00985517 ↗

NCT00252850 ↗

Known as AAV2-NTN “CERE-120: AAV2-NTN” NCT00252850 ↗
Modality Gene therapy (AAV / viral vector) “in vivo AAV2 mediated delivery of the gene encoding NTN (CERE-120)” NCT00252850 ↗
Route Other “bilateral, stereotactic, intraputaminal injections of adeno-associated virus serotype 2-neurturin (CERE-120)” PMID 18387850 ↗ Apr 2008