Drugs / Topiroxostat
last change Mar 2018 re-read 2 minutes ago

Topiroxostat

also known as FYX-051

Small molecule targets XDH via inhibition

Developed for
diabetic kidney disease
Investigated by
Fuji Yakuhin Co., Ltd.

Trials 1 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02837198 Jul 2016 → Aug 2017 Fuji Yakuhin Co., Ltd. Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02327754 Comparator ? → Dec 2016 diabetic kidney disease Sanwa Kagaku Kenkyusho Co., Ltd. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Topiroxostat ClinicalTrials.gov intervention name — accepted as the source's own label NCT02837198
1

NCT02327754

Known as FYX-051 ChEMBL registry synonym — accepted as the source's own label CHEMBL1078685
Action Inhibit “Xanthine dehydrogenase inhibitor” CHEMBL1078685
Modality Small molecule CHEMBL1078685
Route Oral Oral daily dosing for 28 weeks” NCT02327754
Target XDH “Xanthine dehydrogenase inhibitor” CHEMBL1078685