Drugs / Topiroxostat
last change Mar 2018 re-read 9 days ago

Topiroxostat

also known as FYX-051

Small molecule targets XDH via inhibition

Developed for
diabetic kidney disease
Investigated by
Fuji Yakuhin Co., Ltd.

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT02837198 Jul 2016 → Aug 2017 — Fuji Yakuhin Co., Ltd. Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT02327754 Comparator ? → Dec 2016 diabetic kidney disease Sanwa Kagaku Kenkyusho Co., Ltd. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Topiroxostat ClinicalTrials.gov intervention name — accepted as the source's own label NCT02327754 ↗
1

NCT02837198 ↗

Known as FYX-051 ChEMBL registry synonym — accepted as the source's own label CHEMBL1078685 ↗
Action Inhibit “Xanthine dehydrogenase inhibitor” CHEMBL1078685 ↗
Modality Small molecule — CHEMBL1078685 ↗
Route Oral “Oral daily dosing for 28 weeks” NCT02327754 ↗
Target XDH “Xanthine dehydrogenase inhibitor” CHEMBL1078685 ↗