Drugs / TY-9591
last change Jun 2025 re-read 2 minutes ago

TY-9591

also known as asandeutertinib
Developed for
non-small cell lung carcinoma · metastatic malignant neoplasm in the brain · neoplastic meningitis
Investigated by
TYK Medicines, Inc

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT05871905 Jun → Nov 2023 TYK Medicines, Inc Completed No outcome recorded
Phase 1 NCT04798638 Apr → Sep 2021 TYK Medicines, Inc Completed No outcome recorded
Phase 1 NCT04204473 May 2020 → Mar 2023 non-small cell lung carcinoma TYK Medicines, Inc Completed No outcome recorded
Phase 23 trials
Phase 2 NCT06672068 Feb 2025 → Dec 2027 expected non-small cell lung carcinoma TYK Medicines, Inc Not yet recruiting No outcome recorded
Phase 2 NCT05948813 Aug 2023 → Jun 2025 overdue metastatic malignant neoplasm in the brain, non-small cell lung carcinoma TYK Medicines, Inc Recruiting No outcome recorded
Phase 2 NCT05146219 Apr 2022 → Mar 2024 metastatic malignant neoplasm in the brain, neoplastic meningitis, non-small cell lung carcinoma TYK Medicines, Inc Completed No outcome recorded
Phase 31 trial
Phase 3 NCT05382728 Jun 2022 → May 2025 overdue non-small cell lung carcinoma TYK Medicines, Inc Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as TY-9591 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05871905
6

NCT05948813

NCT05146219

NCT04204473

NCT04798638

NCT05382728

NCT06672068

Known as asandeutertinib “This phase 1 study evaluated the safety, pharmacokinetics, and preliminary efficacy of TY-9591 (asandeutertinib), a deuterated osimertinib derivative.” PMID 39929334 Feb 2025
Route Oral “multiple doses of TY-9591 administered orally once daily” NCT04204473