Drugs / SPH4336
last change May 2026 re-read 2 minutes ago

SPH4336

targets CDK4 via inhibition

Developed for
breast cancer · cancer · dedifferentiated liposarcoma · metastatic malignant neoplasm in the brain
Investigated by
Shanghai Pharmaceuticals Holding Co., Ltd · Shanghai Pharma Biotherapeutics USA Inc.

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/22 trials
Phase 1/2 NCT05944224 Oct 2023 → May 2026 overdue cancer Shanghai Pharmaceuticals Holding Co., Ltd Recruiting No outcome recorded
Phase 1/2 NCT05905614 Nov 2020 → Oct 2023 cancer Shanghai Pharmaceuticals Holding Co., Ltd Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05872347 Sep 2023 → Dec 2026 expected metastatic malignant neoplasm in the brain Shanghai Pharmaceuticals Holding Co., Ltd Recruiting No outcome recorded
Phase 2 NCT05580588 Aug 2023 → Oct 2024 dedifferentiated liposarcoma Shanghai Pharma Biotherapeutics USA Inc. Terminated No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT05860465 Sep 2023 → Dec 2026 expected breast cancer Shanghai Pharmaceuticals Holding Co., Ltd Recruiting No outcome recorded
Phase 2/3 NCT05744687 Apr 2023 → May 2026 overdue breast cancer Shanghai Pharmaceuticals Holding Co., Ltd Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as SPH4336 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05860465
5

NCT05905614

NCT05744687

NCT05580588

NCT05872347

NCT05944224

Action Inhibit “CDK4/6 inhibitor” NCT05580588
Route Oral “will be administered orally once each day” NCT05580588
Target CDK4 CDK4/6 inhibitor” NCT05580588