Drugs / Luxdegalutamide
last change Nov 2025 re-read 2 minutes ago

Luxdegalutamide

also known as JSB462 · Luxdegalutamida

Small molecule

Developed for
castration-resistant prostate carcinoma · metastatic prostate carcinoma
Investigated by
Novartis Pharmaceuticals

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07174063 Nov 2025 → Jan 2027 expected metastatic prostate carcinoma Novartis Pharmaceuticals Active not recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT07206056 Oct 2025 → Nov 2029 expected castration-resistant prostate carcinoma Novartis Pharmaceuticals Recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT06991556 Jul 2025 → Mar 2032 expected metastatic prostate carcinoma Novartis Pharmaceuticals Recruiting No outcome recorded
Phase 2 NCT07047118 Jul 2025 → Jul 2027 expected castration-resistant prostate carcinoma Novartis Pharmaceuticals Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Luxdegalutamide “A Phase I Study of JSB462 (Luxdegalutamide) in Japanese Patients With Metastatic Prostate Cancer” NCT07174063
Known as JSB462 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07047118
3

NCT06991556

NCT07206056

NCT07174063

Known as Luxdegalutamida ChEMBL registry synonym — accepted as the source's own label CHEMBL5314528
Modality Small molecule CHEMBL5314528
Route Oral “JSB462 is administered from randomization, orally, daily and continuously (100 mg or 300 mg QD) until disease progression per PCWG3-modified RECIST 1.1 as assessed by the...” NCT06991556