Drugs / ADOPRAZINE
last change May 2008 re-read 3 minutes ago

ADOPRAZINE

also known as SLV-313 · Adoprazina

Small molecule targets DRD2, DRD3, HTR1A via inhibition / activation

Investigated by
Solvay Pharmaceuticals · Wyeth is now a wholly owned subsidiary of Pfizer

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00620568 Feb → Mar 2008 — Wyeth is now a wholly owned subsidiary of Pfizer Terminated No outcome recorded
Phase 1 NCT00581243 Jan → May 2008 — Wyeth is now a wholly owned subsidiary of Pfizer Terminated No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as ADOPRAZINE ChEMBL registry synonym — accepted as the source's own label CHEMBL221692 ↗
Known as Adoprazina ChEMBL registry synonym — accepted as the source's own label CHEMBL221692 ↗
Known as SLV-313 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00620568 ↗
1

NCT00581243 ↗

Action Activate “Serotonin 1a (5-HT1a) receptor agonist” CHEMBL221692 ↗
Action Inhibit “Dopamine D2 receptor antagonist” CHEMBL221692 ↗
1

“Dopamine D3 receptor antagonist” CHEMBL221692 ↗

Modality Small molecule — CHEMBL221692 ↗
Route Oral “Administered Orally” NCT00581243 ↗
Target DRD2 “Dopamine D2 receptor antagonist” CHEMBL221692 ↗
Target DRD3 “Dopamine D3 receptor antagonist” CHEMBL221692 ↗
Target HTR1A “Serotonin 1a (5-HT1a) receptor agonist” CHEMBL221692 ↗