Phase 0 2 trials
Phase 0
NCT02659241
Feb 2016 → Dec 2026 expected
fallopian tube serous adenocarcinoma , ovarian serous adenocarcinoma , primary peritoneal serous adenocarcinoma
M.D. Anderson Cancer Center
Active not recruiting
No outcome recorded
Phase 0
NCT02207010
Jul 2014 → Dec 2015
glioblastoma
St. Joseph's Hospital and Medical Center, Phoenix
Completed
No outcome recorded
Phase 1 27 trials
Phase 1
NCT05008913
Oct → Nov 2021
cancer
AstraZeneca
Terminated
No outcome recorded
Phase 1
NCT04949425
Sep 2021 → Apr 2022
cancer
AstraZeneca
Terminated
No outcome recorded
Phase 1
NCT04959266
Jun 2021 → Jun 2022
cancer
AstraZeneca
Terminated
No outcome recorded
Phase 1
NCT04460937
Apr 2021 → Mar 2024 overdue
esophageal adenocarcinoma , esophageal squamous cell carcinoma , gastric cardia adenocarcinoma , gastroesophageal junction adenocarcinoma +2
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT04197713
Jun 2020 → Feb 2023 overdue
metastatic malignant neoplasm
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT04462952
Jun 2020 → Sep 2021
neoplasm
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT03345784
May 2018 → May 2022
cervical carcinoma , endometrioid adenocarcinoma , uterine corpus cancer , vaginal carcinoma
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 1
NCT03333824
Dec 2017 → Jan 2019
cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT03313557
Oct 2017 → May 2019
cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT03315091
Sep 2017 → Apr 2018
cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT03028766
Jun 2017 → Oct 2019
hypopharynx squamous cell carcinoma , larynx cancer , oral cavity squamous cell carcinoma
University of Birmingham
Completed
No outcome recorded
Phase 1
NCT02791919
May 2017 → May 2019
aneurysm, intracranial berry, 2 , childhood acute myeloid leukemia
National Cancer Institute (NCI)
Withdrawn
No outcome recorded
Phase 1
NCT02546661
Dec 2016 → Mar 2020 overdue
infiltrating bladder urothelial carcinoma
AstraZeneca
Active not recruiting
No outcome recorded
Phase 1
NCT02906059
Sep 2016 → Mar 2020
colorectal cancer
NYU Langone Health
Completed
No outcome recorded
Phase 1
NCT02617277
Dec 2015 → Apr 2019
cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT02610075
Dec 2015 → Apr 2018
metastatic neoplasm , ovarian cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT02585973
Oct 2015 → Jun 2019
head and neck squamous cell carcinoma
UNC Lineberger Comprehensive Cancer Center
Completed
No outcome recorded
Phase 1
NCT02381548
Aug 2015 → May 2018
blast phase chronic myelogenous leukemia, BCR-ABL1 positive , myelodysplastic syndrome , therapy related acute myeloid leukemia and myelodysplastic syndrome
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 1
NCT02511795
Aug 2015 → Apr 2019
refractory malignant neoplasm , small cell lung carcinoma
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT02508246
Jul 2015 → Apr 2018
head and neck squamous cell carcinoma
University of Washington
Completed
No outcome recorded
Phase 1
NCT02482311
Jul 2015 → Jan 2018
—
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT02341456
Jan 2015 → Dec 2016
cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT01849146
Oct 2013 → Jul 2021
glioblastoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01922076
Sep 2013 → Dec 2020
anaplastic astrocytoma , anaplastic oligoastrocytoma , diffuse midline glioma, H3 K27M-mutant , gliosarcoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01748825
Dec 2012 → May 2020
cancer
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01047007
Jan 2010 → Jun 2011
cancer
Merck Sharp & Dohme LLC
Terminated
No outcome recorded
Phase 1
NCT00648648
Feb 2008 → Jan 2014
cancer
Merck Sharp & Dohme LLC
Completed
No outcome recorded
Show 17 more trials
Phase 1/2 5 trials
Phase 1/2
NCT02813135
Aug 2016 → Feb 2031 expected
childhood malignant neoplasm
Gustave Roussy, Cancer Campus, Grand Paris
Recruiting
No outcome recorded
Phase 1/2
NCT02194829
Aug 2014 → Jun 2021
pancreatic adenocarcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1/2
NCT02095132
Mar 2014 → Dec 2020
childhood supratentorial embryonal tumor with multilayered rosettes, C19MC-altered , ganglioneuroblastoma , medulloblastoma , neuroblastoma +3
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1/2
NCT02037230
Jan 2014 → Aug 2018
pancreatic adenocarcinoma
University of Michigan Rogel Cancer Center
Completed
No outcome recorded
Phase 1/2
NCT01076400
May 2010 → Jun 2011
cervical cancer
Merck Sharp & Dohme LLC
Terminated
No outcome recorded
Phase 2 26 trials
Phase 2
NCT05212025
Jun 2022 → Jun 2023
malignant pancreatic neoplasm
James Cleary, MD, PhD
Withdrawn
No outcome recorded
Phase 2
NCT04590248
Nov 2020 → May 2022
endometrial serous adenocarcinoma
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT03718143
May → Sep 2019
acute myeloid leukemia , myelodysplastic syndrome , myelofibrosis
NYU Langone Health
Terminated
No outcome recorded
Phase 2
NCT03284385
Jan 2019 → Mar 2026 overdue
clear cell renal carcinoma , metastatic malignant neoplasm
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT03253679
Jan 2019 → Oct 2022
high grade malignant neoplasm
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT03579316
Dec 2018 → Dec 2026 expected
fallopian tube carcinoma , ovarian carcinoma , primary peritoneal carcinoma
M.D. Anderson Cancer Center
Active not recruiting
No outcome recorded
Phase 2
NCT03668340
Oct 2018 → Jul 2026 overdue
uterine cancer
Dana-Farber Cancer Institute
Active not recruiting
No outcome recorded
Phase 2
NCT03385655
Aug 2018 → Oct 2024 overdue
prostate cancer
Canadian Cancer Trials Group
Active not recruiting
No outcome recorded
Phase 2
NCT02666950
May 2017 → Sep 2018
acute myeloid leukemia , chronic myelomonocytic leukemia , myelodysplastic syndrome associated with isolated del(5q)
Mayo Clinic
Completed
No outcome recorded
Phase 2
NCT04439227
Mar 2017 → Dec 2026 expected
adult lymphoma , plasma cell myeloma , refractory malignant neoplasm
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT03012477
Jan 2017 → May 2019
triple-negative breast carcinoma
Dana-Farber Cancer Institute
Completed
No outcome recorded
Phase 2
NCT02937818
Nov 2016 → Jun 2020
—
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT02688907
Jun 2016 → Dec 2017
small cell lung carcinoma
Samsung Medical Center
Terminated
No outcome recorded
Phase 2
NCT02593019
Dec 2015 → Oct 2018
small cell lung carcinoma
Samsung Medical Center
Completed
No outcome recorded
Phase 2
NCT02576444
Nov 2015 → Nov 2019
cancer
Joseph Paul Eder
Terminated
No outcome recorded
Phase 2
NCT02513563
Oct 2015 → Nov 2022
lung cancer
H. Lee Moffitt Cancer Center and Research Institute
Completed
No outcome recorded
Phase 2
NCT02465060
Aug 2015 → Dec 2026 expected
breast carcinoma , carcinoma of esophagus , cervical carcinoma , colon carcinoma +17
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT02272790
Jan 2015 → Dec 2018
neoplastic disease or syndrome
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT02448329
Jan 2015 → Dec 2019
gastric adenocarcinoma
Samsung Medical Center
Completed
No outcome recorded
Phase 2
NCT02101775
Jul 2014 → Feb 2022 overdue
fallopian tube carcinoma , ovarian Brenner tumor , ovarian carcinosarcoma , ovarian clear cell cystadenocarcinoma +7
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT02087176
Mar 2014 → May 2015
non-small cell lung carcinoma
AstraZeneca
Terminated
No outcome recorded
Phase 2
NCT02196168
Mar 2014 → Apr 2016
hypopharynx squamous cell carcinoma , larynx verrucous carcinoma , metastatic squamous cell carcinoma , nasal cavity and paranasal sinus squamous cell carcinoma +3
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 2
NCT02087241
Mar 2014 → Jun 2015
—
AstraZeneca
Terminated
No outcome recorded
Phase 2
NCT01827384
Jan 2014 → Jun 2021
cancer
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01357161
Jul 2011 → Aug 2016
ovarian cancer
Merck Sharp & Dohme LLC
Completed
No outcome recorded
Phase 2
NCT01164995
Jul 2010 → Apr 2023
malignant epithelial tumor of ovary
The Netherlands Cancer Institute
Completed
No outcome recorded
Show 16 more trials