Drugs / Talacotuzumab
last change Oct 2021 re-read 2 minutes ago

Talacotuzumab

also known as JNJ-56022473 · CSL362

Monoclonal antibody targets IL3RA

Developed for
acute myeloid leukemia · myelodysplastic syndrome · systemic lupus erythematosus
Investigated by
Janssen Research & Development, LLC · CSL Limited · GWT-TUD GmbH · Parexel

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02920424 Jun 2017 → Feb 2019 systemic lupus erythematosus Janssen Research & Development, LLC Withdrawn No outcome recorded
Phase 1 NCT01632852 Jul 2012 → Aug 2015 acute myeloid leukemia CSL Limited Completed No outcome recorded
Phase 22 trials
Phase 2 NCT03011034 Feb 2017 → Jan 2019 myelodysplastic syndrome Janssen Research & Development, LLC Completed No outcome recorded
Phase 2 NCT02992860 Jul 2016 → Oct 2018 acute myeloid leukemia, myelodysplastic syndrome GWT-TUD GmbH Terminated No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02472145 Aug 2015 → Jan 2018 acute myeloid leukemia Janssen Research & Development, LLC Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Talacotuzumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT02472145
1

NCT03011034

Known as CSL362 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01632852
Known as JNJ-56022473 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02920424
1

NCT02992860

Modality Monoclonal antibody “CSL362 is humanized monoclonal antibodyNCT01632852
Route Intravenous “administered by intravenous infusion” NCT01632852
Target IL3RA “CSL362 is humanized monoclonal antibody that targets the alpha chain of the interleukin 3 receptor (IL3Rα; also known as CD123)” NCT01632852