Drugs / Duvoglustat
Duvoglustat
also known as
1 deoxynojirimycin · 1 deoxynojirimycin hydrochloride · 1,5-dideoxy-1,5-imino- · 1,5-dideoxy-1,5-imino-d-glucitol · 1-dnj · AT-2220 · Bay-h-5595 · D-1-deoxynojirimycin · +6 more
Small molecule targets GAA
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT01380743 | Oct 2011 → Jan 2013 | glycogen storage disease II | Amicus Therapeutics | Completed | No outcome recorded |
| Phase 2 | NCT00688597 | Dec 2008 → Dec 2009 | glycogen storage disease II | Amicus Therapeutics | Terminated | No outcome recorded |
Evidence & citations 19 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Duvoglustat | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00688597 ↗ |
| Known as | 1 deoxynojirimycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | 1 deoxynojirimycin hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | 1,5-dideoxy-1,5-imino- | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | 1,5-dideoxy-1,5-imino-d-glucitol | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | 1-dnj | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | AT-2220 | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | Bay-h-5595 | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | D-1-deoxynojirimycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | Deoxynojirimycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | Duvoglustat hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | DUVOGLUSTAT HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | Moranolin | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | Moranoline | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Known as | Moranoline hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL307429 ↗ |
| Action | Restore | “Duvoglustat is designed to act as a pharmacological chaperone of alpha-glucosidase, in order to restore enzyme activity.” NCT00688597 ↗ |
| Modality | Small molecule | — CHEMBL307429 ↗ |
| Route | Oral | “Powder in a bottle for dissolution in water for oral administration” NCT00688597 ↗ |
| Target | GAA | “Lysosomal alpha-glucosidase stabiliser” CHEMBL307429 ↗ |