Drugs / Clostridium novyi-NT

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03435952 Jul 2018 → Oct 2026 expected breast cancer, cancer of unknown primary site, digestive system cancer, female reproductive organ cancer +7 M.D. Anderson Cancer Center Active not recruiting No outcome recorded
Phase 1 NCT01924689 Oct 2013 → Oct 2017 BioMed Valley Discoveries, Inc Completed No outcome recorded
Phase 1 NCT00358397 Jul 2006 → Sep 2008 neoplasm Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Clostridium novyi-NT ClinicalTrials.gov intervention name — accepted as the source's own label NCT00358397
2

NCT03435952

NCT01924689

Known as C. novyi-NT “This first-in-human study (NCT01924689) enrolled patients with injectable, treatment-refractory solid tumors to receive a single intratumoral injection of C. novyi-NT across 6...” PMID 33046513 Oct 2020
1

“This study will include a one time intravenous (IV) infusion of Clostridium novyi-NT (C. novyi-NT) spores to treat solid tumors which have not responded to standard therapy.” NCT00358397

Modality Other / unclassified “Investigators at the SKCCC have developed a bacterial strain (C. novyi-NT) that can infect tumors and destroy them, but does not grow in normal tissues.” NCT00358397
Route Intravenous “one time intravenous (IV) infusion of Clostridium novyi-NT (C. novyi-NT) spores” NCT00358397