Drugs / LY2608204
LY2608204
also known as
SY-004 · Globalagliatin · Globalagliatin Hydrochloride · LY-2608204 HYDROCHLORIDE · SY-004 HYDROCHLORIDE
Small molecule targets GCK via activation
Trials 8 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 16 trials | ||||||
| Phase 1 | NCT04907006 | Aug → Oct 2021 | type 2 diabetes mellitus | Suzhou Yabao Pharmaceutical R&D Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT04907019 | Jul → Aug 2021 | type 2 diabetes mellitus | Suzhou Yabao Pharmaceutical R&D Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT03414892 | Jan 2018 → Jan 2019 | hyperglycemia, type 2 diabetes mellitus | Yabao Pharmaceutical Group | Completed | No outcome recorded |
| Phase 1 | NCT03171623 | Apr → Sep 2017 | hyperglycemia | Yabao Pharmaceutical Group | Completed | No outcome recorded |
| Phase 1 | NCT01313286 | Mar → Apr 2011 | — | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 1 | NCT01247363 | Nov 2010 → Mar 2011 | type 2 diabetes mellitus | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT04217291 | Dec 2019 → Jul 2021 | type 2 diabetes mellitus | Suzhou Yabao Pharmaceutical R&D Co., Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT01408095 | Sep 2011 → Sep 2012 | type 2 diabetes mellitus | Eli Lilly and Company | Withdrawn | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | LY2608204 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01247363 ↗ |
| Known as | Globalagliatin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03414892 ↗ |
| Known as | Globalagliatin Hydrochloride | “Globalagliatin Hydrochloride (SY-004)” NCT03414892 ↗ |
| Known as | LY-2608204 HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297399 ↗ |
| Known as | SY-004 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04907019 ↗ |
| Known as | SY-004 HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297399 ↗ |
| Action | Activate | “Hexokinase type IV activator” CHEMBL4297399 ↗1“Glucokinase Activator” NCT01247363 ↗ |
| Modality | Small molecule | — CHEMBL4297399 ↗ |
| Route | Oral | “Administered orally.” NCT01247363 ↗ |
| Target | GCK | “Hexokinase type IV activator” CHEMBL4297399 ↗ |