Drugs / VIPADENANT
last change Jun 2010 re-read 3 minutes ago

VIPADENANT

Small molecule targets ADORA2A via inhibition

Developed for
Parkinson disease
Investigated by
Biogen

Trials 5

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01035515 Dec 2009 → Apr 2010 — Biogen Completed No outcome recorded
Phase 1 NCT01017666 Nov 2009 → Jun 2010 — Biogen Completed No outcome recorded
Phase 1 NCT00531193 Sep 2007 → Apr 2008 — Biogen Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00438607 Apr 2007 → Apr 2009 Parkinson disease Biogen Completed No outcome recorded
Phase 2 NCT00451815 — Parkinson disease Biogen Withdrawn No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT00442780 Comparator Aug 2007 → Dec 2008 Parkinson disease Biogen Completed No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2010-04-05 Biogen Results Biogen Idec Strengthens Position as a Leader in Neurology with 38 Data Presentations at 62nd Annual Meeting of the American Academy of Neurology biogen.com ↗
2009-03-25 Biogen Results Biogen Idec Highlights Progress and Breadth of Pipeline Programs at R&D Day biogen.com ↗
Interim results from this study were favorable and support continued development of BIIB014 in this setting.

Evidence & citations 12 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as VIPADENANT ChEMBL registry synonym — accepted as the source's own label CHEMBL447664 ↗
Known as BIIB014 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00451815 ↗
5

NCT00531193 ↗

NCT01017666 ↗

NCT00438607 ↗

NCT01035515 ↗

NCT00442780 ↗

Known as CEB-4520 ChEMBL registry synonym — accepted as the source's own label CHEMBL447664 ↗
Known as V-2006 ChEMBL registry synonym — accepted as the source's own label CHEMBL447664 ↗
Known as VER-11135 ChEMBL registry synonym — accepted as the source's own label CHEMBL447664 ↗
Known as VER-A-00-11 ChEMBL registry synonym — accepted as the source's own label CHEMBL447664 ↗
Known as VER-A-00049 ChEMBL registry synonym — accepted as the source's own label CHEMBL447664 ↗
Known as VER-ADO-49 ChEMBL registry synonym — accepted as the source's own label CHEMBL447664 ↗
Action Inhibit “Adenosine A2a receptor antagonist” CHEMBL447664 ↗
Modality Small molecule — CHEMBL447664 ↗
Route Oral “oral administration of BIIB014” NCT00438607 ↗
Target ADORA2A “Adenosine A2a receptor antagonist” CHEMBL447664 ↗