Drugs / FAZPILODEMAB
last change Jan 2023 re-read 3 minutes ago

FAZPILODEMAB

also known as BFKB8488A · RG-7992 · RO-7040551

Monoclonal antibody

Developed for
metabolic dysfunction-associated steatohepatitis · NAFLD1 · type 2 diabetes mellitus
Investigated by
Genentech, Inc.

Trials 3

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03060538 Mar 2017 → Dec 2019 NAFLD1, type 2 diabetes mellitus Genentech, Inc. Completed No outcome recorded
Phase 1 NCT02593331 Oct 2015 → Mar 2017 — Genentech, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04171765 Sep 2020 → Jan 2023 metabolic dysfunction-associated steatohepatitis Genentech, Inc. Terminated No outcome recorded Stop: Business

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as FAZPILODEMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4297909 ↗
Known as BFKB8488A ClinicalTrials.gov intervention name — accepted as the source's own label NCT04171765 ↗
2

NCT02593331 ↗

NCT03060538 ↗

Known as RG-7992 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297909 ↗
Known as RO-7040551 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297909 ↗
Action Activate “Fibroblast growth factor receptor 1/Klothoβ agonist BFKB8488A” PMID 35993161 ↗ Sep 2022
Modality Monoclonal antibody — CHEMBL4297909 ↗
Route Subcutaneous “administered SC” NCT02593331 ↗