Drugs / PERAMIVIR ANHYDROUS
PERAMIVIR ANHYDROUS
also known as
Peramivir · Alpivab · BCX1812 · Peramivir hydrate · Peramivir trihydrate · Rapiacta · RAPIVAB · RWJ-270201 · +1 more
Regulatory milestones approvals, filings & regulatory actions · 4 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansions (2) | US (FDA) | RAPIVAB | — | 2017-09-20 – 2021-01-28 | fda.gov ↗ |
| Approved | EU (EMA) | Alpivab | — | 2018-04-13 | europa.eu ↗ |
| Approved | US (FDA) | RAPIVAB | — | 2014-12-19 | fda.gov ↗ |
Trials 14 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00297050 | Feb → Nov 2006 | influenza | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT01063933 | ? → Aug 2011 | influenza | National Institute of Allergy and Infectious Diseases (NIAID) | Withdrawn | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT05648448 | Feb 2023 → Jan 2027 expected | influenza | University of Oxford | Recruiting | No outcome recorded |
| Phase 2 | NCT00705406 | Jul 2008 → Apr 2009 | influenza | BioCryst Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00453999 | Jul 2007 → Sep 2008 | influenza | BioCryst Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT00419263 | Jan → Sep 2007 | influenza | BioCryst Pharmaceuticals | Completed | No outcome recorded |
| Phase 37 trials | ||||||
| Phase 3 | NCT02635724 | Dec 2015 → Apr 2018 | influenza | BioCryst Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT02369159 | Mar 2015 → Oct 2019 | influenza | BioCryst Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT01224795 | Oct → Nov 2010 | influenza | BioCryst Pharmaceuticals | Withdrawn | No outcome recorded |
| Phase 3 | NCT00958776 | Nov 2009 → Nov 2012 | headache disorder, influenza, nasal cavity disorder, pharyngitis | BioCryst Pharmaceuticals | Terminated | No outcome recorded |
| Phase 3 | NCT00957996 | Oct 2009 → Oct 2010 | headache disorder, influenza, nasal cavity disorder, pharyngitis | BioCryst Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00610935 | Jan → Feb 2008 | influenza | BioCryst Pharmaceuticals | Terminated | No outcome recorded |
| Phase 3 | NCT00486980 | — | influenza | BioCryst Pharmaceuticals | Withdrawn | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT02609399 | Nov 2015 → May 2017 | influenza | Johns Hopkins University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2/3 | NCT02665351 Comparator | Feb 2011 → Mar 2014 | influenza | Chinese University of Hong Kong | Completed | No outcome recorded |
Evidence & citations 13 cited values
Every value below carries the sentence it was read from. 16 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | PERAMIVIR ANHYDROUS | ChEMBL registry synonym — accepted as the source's own label CHEMBL139367 ↗ |
| Known as | Alpivab | ChEMBL registry synonym — accepted as the source's own label CHEMBL139367 ↗ |
| Known as | BCX1812 | “Placebo Peramivir (BCX1812) administered intravenously” NCT00958776 ↗ |
| Known as | Peramivir | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02665351 ↗ |
| Known as | Peramivir hydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL139367 ↗ |
| Known as | Peramivir trihydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL139367 ↗ |
| Known as | Rapiacta | ChEMBL registry synonym — accepted as the source's own label CHEMBL139367 ↗ |
| Known as | RAPIVAB | “Peramivir (RAPIVAB®)” NCT05648448 ↗ |
| Known as | RWJ-270201 | ChEMBL registry synonym — accepted as the source's own label CHEMBL139367 ↗ |
| Known as | RWJ-270201-162 ANHYDROUS | ChEMBL registry synonym — accepted as the source's own label CHEMBL139367 ↗ |
| Action | Inhibit | “intravenous peramivir, a neuraminidase inhibitor” NCT00297050 ↗ |
| Modality | Small molecule | — CHEMBL139367 ↗ |
| Route | Intravenous | “intravenous peramivir” NCT00297050 ↗ |