Drugs / iTreg
iTreg
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT01634217 | Nov 2013 → Dec 2017 | Hodgkins lymphoma, acute myeloid leukemia, chronic lymphocytic leukemia/small lymphocytic lymphoma, chronic myeloid leukemia +2 | Masonic Cancer Center, University of Minnesota | Completed | No outcome recorded |
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2025-03-28 | Chugai Pharmaceutical | Results Joint Research Results on Regulatory T cells between Osaka University Immunology Frontier Research Center and Chugai Published in Nature chugai-pharm.co.jp ↗
This study is the first to elucidate the regulatory network of FoxP3, a master transcription factor essential for maintaining Treg function, in human induced regulatory T cells (iTreg), and proposes the possibility of new autoimmune disease treatment through Treg regulation. |
All press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2025-03-28 | Chugai Pharmaceutical | Joint Research Results on Regulatory T cells between Osaka University Immunology Frontier Research Center and Chugai Published in Nature chugai-pharm.co.jp ↗ |
Evidence & citations 4 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | iTreg | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01634217 ↗ |
| Known as | induced regulatory T cells | “Human CD4+25- T cells cultured in interleukin 2 (IL-2), rapamycin, and transforming growth factor β (TGFβ) along with anti-CD3 monoclonal antibody-loaded artificial...” PMID 33666654 ↗ Mar 2021 |
| Known as | iTregs | “Human CD4+25- T cells cultured in interleukin 2 (IL-2), rapamycin, and transforming growth factor β (TGFβ) along with anti-CD3 monoclonal antibody-loaded artificial...” PMID 33666654 ↗ Mar 2021 |
| Modality | Cell therapy | “induced regulatory T cells” PMID 33666654 ↗ Mar 2021 |