Drugs / 177Lu-edotreotide
last change Apr 2025 re-read 2 minutes ago

177Lu-edotreotide

Peptide targets SSTR2

Developed for
neuroendocrine neoplasm · lung neuroendocrine neoplasm · thymus neoplasm
Investigated by
ITM Solucin GmbH · ABX CRO · ITM Oncologics GmbH · MFAR · PSI CRO · Spanish Group for Research in Neuroendocrine Tumors

Trials 3 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT05918302 Oct 2023 → Mar 2029 expected lung neuroendocrine neoplasm, thymus neoplasm Spanish Group for Research in Neuroendocrine Tumors Recruiting No outcome recorded
Phase 3 NCT04919226 Dec 2021 → Jun 2027 expected neuroendocrine neoplasm ITM Solucin GmbH Active not recruiting No outcome recorded
Phase 3 NCT03049189 Feb 2017 → Nov 2024 overdue neuroendocrine neoplasm ITM Solucin GmbH Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as 177Lu-edotreotide ClinicalTrials.gov intervention name — accepted as the source's own label NCT05918302
2

NCT04919226

NCT03049189

Known as (177)Lutetium[Lu]-edotreotide “A Randomized clinical trial evaluating the impact on survival and quality of life of (177)Lutetium[Lu]-edotreotide versus everolimus in patients with neuroendocrine tumors of...” PMID 40186126 Apr 2025
Modality Peptide Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-Edotreotide” NCT04919226
Route Intravenous “Route of administration: Slow intravenous infusion/injection (i.v.)” NCT03049189
Target SSTR2 “Retrospective data suggest a potential meaningful benefit of RLT directed to SSTR2 in lung-NET patients.” PMID 40186126 Apr 2025