Drugs / Neosaxitoxin
last change Sep 2018 re-read 2 minutes ago

Neosaxitoxin

also known as NeoSTX

Small molecule

Investigated by
Charles Berde · Grünenthal GmbH · University of Chile

Trials 3 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03399435 Jan → Sep 2018 Grünenthal GmbH Terminated No outcome recorded
Phase 1 NCT01786655 May 2013 → Mar 2014 Charles Berde Completed No outcome recorded
Phase 1 NCT00273065 May → Sep 2005 University of Chile Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Neosaxitoxin ClinicalTrials.gov intervention name — accepted as the source's own label NCT00273065
2

NCT03399435

NCT01786655

Known as NeoSTX “Neosaxitoxin (NeoSTX) Alone and in Combination With Bupivacaine as Prolonged Duration Local Anesthetics: A Phase I Investigator-initiated Dose Escalation Study” NCT01786655
Action Inhibit “reversible block the voltage-gated sodium channels at neuronal level” NCT00273065
Modality Small molecule CHEMBL4297307
Route Subcutaneous Subcutaneous injections were made in the middle posterior skin of the calf” PMID 17264729 Feb 2007