Drugs / Neosaxitoxin
last change Sep 2018 re-read 9 days ago

Neosaxitoxin

also known as NeoSTX

Small molecule

Investigated by
Charles Berde · Grünenthal GmbH · University of Chile

Trials 3

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03399435 Jan → Sep 2018 — Grünenthal GmbH Terminated No outcome recorded
Phase 1 NCT01786655 May 2013 → Mar 2014 — Charles Berde Completed No outcome recorded
Phase 1 NCT00273065 May → Sep 2005 — University of Chile Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Neosaxitoxin ClinicalTrials.gov intervention name — accepted as the source's own label NCT00273065 ↗
2

NCT03399435 ↗

NCT01786655 ↗

Known as NeoSTX “Neosaxitoxin (NeoSTX) Alone and in Combination With Bupivacaine as Prolonged Duration Local Anesthetics: A Phase I Investigator-initiated Dose Escalation Study” NCT01786655 ↗
Action Inhibit “reversible block the voltage-gated sodium channels at neuronal level” NCT00273065 ↗
Modality Small molecule — CHEMBL4297307 ↗
Route Subcutaneous “Subcutaneous injections were made in the middle posterior skin of the calf” PMID 17264729 ↗ Feb 2007