Drugs / 225Ac-PSMA-Trillium
last change Feb 2026 re-read 3 minutes ago

225Ac-PSMA-Trillium

also known as BAY3563254
Developed for
castration-resistant prostate carcinoma
Investigated by
Bayer

Trials 1

20252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06217822 Mar 2024 → Nov 2028 expected castration-resistant prostate carcinoma Bayer Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-02-27 Bayer Results Bayer reports encouraging results for next generation investigational targeted radionuclide therapy 225Ac-PSMA-Trillium in advanced metastatic prostate cancer bayer.com ↗
The dose for expansion was successfully identified, with ≥80% of patients achieving a PSA50 response at the expansion dose.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as 225Ac-PSMA-Trillium ClinicalTrials.gov intervention name — accepted as the source's own label NCT06217822 ↗
Known as BAY3563254 “The study treatment 225Ac-PSMA-Trillium, also called BAY3563254, is under development to treat advanced metastatic castration-resistant prostate cancer.” NCT06217822 ↗
Route Intravenous “Intravenous slow injection on Day 1 of a 6 week treatment cycle.” NCT06217822 ↗