Drugs / AXER-204
last change Aug 2023 re-read 3 minutes ago

AXER-204

Protein / enzyme biologic

Developed for
spinal cord injury
Investigated by
ReNetX Bio, Inc.

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT03989440 Jul 2019 → Jun 2022 spinal cord injury ReNetX Bio, Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AXER-204 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03989440 ↗
Action Inhibit “Soluble Nogo-Receptor-Fc decoy (AXER-204) blocks inhibitors of axon growth and promotes recovery of motor function after SCI in animals.” PMID 37479373 ↗ Aug 2023
Modality Protein / enzyme biologic “AXER-204 is a human fusion protein that acts as a soluble decoy/trap for the myelin-associated inhibitors of axonal growth known as Nogo-A, MAG, and OMgp.” NCT03989440 ↗
Route Intrathecal “AXER-204 was delivered open label as single intrathecal doses of 3 mg, 30 mg, 90 mg, or 200 mg” PMID 37479373 ↗ Aug 2023