Drugs / Angiocal®
last change Dec 2013 re-read 3 minutes ago

Angiocal®

also known as PRS-050 · PRS-050-PEG40

Protein / enzyme biologic targets VEGFA via inhibition

Developed for
cancer
Investigated by
FGK Clinical Research GmbH · Pieris Pharmaceuticals GmbH

Trials 1

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01141257 May 2010 → Sep 2011 cancer Pieris Pharmaceuticals GmbH Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Angiocal ClinicalTrials.gov intervention name — accepted as the source's own label NCT01141257 ↗
Known as PRS-050 “First-in-human phase I study of PRS-050 (Angiocal), an Anticalin targeting and antagonizing VEGF-A, in patients with advanced solid tumors.” PMID 24349470 ↗ Dec 2013
Known as PRS-050-PEG40 “Angiocal® (PRS-050-PEG40)” NCT01141257 ↗
Action Inhibit “targets and antagonizes vascular endothelial growth factor A (VEGF-A)” PMID 24349470 ↗ Dec 2013
Modality Protein / enzyme biologic “a novel, rationally engineered Anticalin based on human tear lipocalin” PMID 24349470 ↗ Dec 2013
Route Intravenous “administered intravenously to patients with solid tumors” NCT01141257 ↗
Target VEGFA “targets and antagonizes vascular endothelial growth factor A (VEGF-A)” PMID 24349470 ↗ Dec 2013