Drugs / AFA-281
last change Jul 2026 re-read 3 minutes ago

AFA-281

Small molecule

Developed for
alcohol abuse · alcohol dependence · radiculopathy
Investigated by
Afasci Inc · Cognitive Research Corporation

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05547503 Apr 2023 → Dec 2024 inflammatory disease, neuropathy, painful Afasci Inc Completed No outcome recorded
Comparator or background therapy3 trials
Phase 1 NCT06719908 Comparator Jul 2025 → Jul 2026 overdue alcohol-related disorders Afasci Inc Not yet recruiting No outcome recorded
Phase 2 NCT06649747 Comparator Apr 2027 → Mar 2032 expected radiculopathy Afasci Inc Not yet recruiting No outcome recorded
Phase 2 NCT06710431 Comparator Oct 2025 → Jun 2027 expected alcohol abuse, alcohol dependence, anxiety, depressive disorder +1 Afasci Inc Not yet recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as AFA-281 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06649747 ↗
3

NCT06710431 ↗

NCT06719908 ↗

NCT05547503 ↗

Modality Small molecule “A small molecule, orally available” NCT06649747 ↗
Route Oral “Oral capsules will be administered in dose titration and split daily dose in fours time daily (QID) for 14 - 21 consecutive days.” NCT05547503 ↗