Drugs / Verubulin
last change Mar 2012 re-read 2 minutes ago

Verubulin

Small molecule

Developed for
glioblastoma · brain neoplasm · metastatic melanoma · refractory malignant neoplasm
Investigated by
Myrexis Inc.

Trials 6 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00393965 Dec 2005 → Aug 2007 brain neoplasm Myrexis Inc. Completed No outcome recorded
Phase 1 NCT00394446 Mar 2005 → Apr 2007 refractory malignant neoplasm Myrexis Inc. Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT00635557 Mar 2008 → Oct 2010 glioblastoma Myrexis Inc. Unknown No outcome recorded
Phase 1/2 NCT00609011 Mar 2008 → Aug 2009 metastatic melanoma Myrexis Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01285414 Dec 2010 → Mar 2012 glioblastoma Myrexis Inc. Completed No outcome recorded
Phase 2 NCT00892931 Apr 2009 → Jul 2011 glioblastoma Myrexis Inc. Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Verubulin Verubulin, dose determined in Part A, i.v. once weekly, Temozolomide \& Radiation Therapy” NCT01285414
Known as Azixa ClinicalTrials.gov intervention name — accepted as the source's own label NCT00892931
Known as MPC-6827 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00609011
3

NCT00394446

NCT00393965

NCT00635557

Known as MX-128495 ChEMBL registry synonym — accepted as the source's own label CHEMBL492399
Known as Verubulin hcl ChEMBL registry synonym — accepted as the source's own label CHEMBL492399
Known as VERUBULIN HYDROCHLORIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL492399
Known as Verubulina ChEMBL registry synonym — accepted as the source's own label CHEMBL492399
Known as Verubuline ChEMBL registry synonym — accepted as the source's own label CHEMBL492399
Modality Small molecule CHEMBL492399
Route Intravenous “2-hour IV infusion” NCT00393965