Drugs / SYN818
last change Jun 2026 re-read 2 minutes ago

SYN818

targets POLQ via inhibition

Developed for
breast cancer · metastatic neoplasm · ovarian cancer · prostate cancer
Investigated by
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07156253 Aug 2025 → Aug 2028 expected breast cancer, metastatic neoplasm, ovarian cancer Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd Recruiting No outcome recorded
Phase 1 NCT06666270 Nov 2024 → Jun 2026 overdue breast cancer, metastatic neoplasm, ovarian cancer, prostate cancer Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as SYN818 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06666270
1

NCT07156253

Action Inhibit “SYN818, a DNA Polymerase Theta (POLQ) Inhibitor” NCT06666270
Route Oral orally receive SYN818” NCT06666270
Target POLQ “SYN818, a DNA Polymerase Theta (POLQ) Inhibitor” NCT06666270